LL‑37 Peptide

Basic Introduction

LL‑37, also known as hCAP‑18, is the only human cathelicidin‑derived antimicrobial peptide naturally produced in the human body. It is a multifunctional bioactive peptide with broad‑spectrum antibacterial, anti‑inflammatory, regenerative, and immunomodulatory properties.

LL‑37 is widely used in advanced skincare, wound healing, anti‑infection therapy, immune regulation, and anti‑aging applications. It is a high‑value cosmetic and medical‑grade peptide raw material supplied by Slimbiotech and SSR Biotechnology, often combined with FOXO4‑DRI, BPC‑157, and TB‑500 for comprehensive skin and tissue repair formulas.

Core Mechanism

LL‑37 directly disrupts the cell membranes of bacteria, fungi, and viruses to eliminate pathogens. It modulates immune cell activity, balances pro‑ and anti‑inflammatory responses, promotes keratinocyte and fibroblast proliferation, accelerates angiogenesis, and stimulates collagen synthesis. Unlike antibiotics, it rarely causes drug resistance.

Key Functions & Core Benefits

1. Broad‑Spectrum Antimicrobial & Antiviral Effect

   Inhibits gram‑positive and gram‑negative bacteria, fungi, and certain enveloped viruses; prevents skin infections, acne, folliculitis, and inflammatory skin conditions; reduces pathogen‑induced tissue damage.

2. Powerful Anti‑Inflammatory & Immune‑Balancing Function

   Regulates excessive inflammatory responses, relieves redness, swelling, itching, and sensitivity; calms chronic skin inflammation such as rosacea and eczema; strengthens local immunity without suppressing normal immune function.

3. Accelerate Wound Healing & Tissue Regeneration

   Promotes skin cell proliferation, collagen synthesis, and new blood vessel formation; speeds up repair of burns, scratches, surgical wounds, and ulcerated tissue; reduces scar formation and shortens recovery time. Synergizes strongly with BPC‑157 for advanced tissue repair.

4. High‑End Skin Rejuvenation & Anti‑Aging

   Improves skin barrier function, enhances moisture retention, reduces fine lines and sagging, brightens dull skin, and fades pigmentation caused by inflammation. It is widely applied in luxury anti‑aging skincare products and peptide injection therapies.

5. Anti‑Acne & Improve Problem Skin

   Eliminates acne‑causing bacteria, reduces sebum over‑secretion, relieves inflammatory acne, and prevents repeated breakouts; improves oily, sensitive, and acne‑prone skin long‑term.

6. Systemic Immune Enhancement

   When administered via injection, it modulates systemic immune activity, reduces chronic low‑grade inflammation, improves body defense ability, and supports anti‑aging longevity programs combined with senolytic peptides like FOXO4‑DRI.

Standard Usage Protocol

• Topical Use: 100–300 ppm added to serums, creams, or masks
• Injectable Use: 1–3 mg per dose, subcutaneous injection, 2–3 times weekly
• Cycle: 4–8 weeks for skin repair or immune regulation
• Solvent: Reconstitute with Sterile Water for Injection (3 mL)

Product Position

LL‑37 is a premium natural human‑derived multifunctional peptide provided by SSR Biotechnology & Slimbiotech, widely used in global medical aesthetics, sensitive skin care, wound care clinics, and anti‑inflammatory anti‑aging peptide formulations.

Research Use Only. This catalog information is reproduced from the customer legacy website. Products are not for human or veterinary use. Confirm current specification, availability and documentation before ordering.