AICAR (5‑Aminoimidazole‑4‑Carboxamide Ribonucleotide)

Basic Introduction

AICAR, chemically named 5‑Aminoimidazole‑4‑Carboxamide Ribonucleotide, is a natural nucleoside metabolite and a potent activator of AMP‑activated protein kinase (AMPK). AMPK is the master metabolic regulator in human cells that controls energy balance, fat burning, mitochondrial function, and cellular longevity.

AICAR is often called an “exercise mimetic peptide/compound” because it triggers the same cellular adaptations as regular physical exercise, even without intense training. It is widely used for fat loss, endurance improvement, metabolic optimization, anti‑aging, and sports performance enhancement, and is a premium performance‑optimizing raw material from Slimbiotech and SSR Biotechnology.

Core Mechanism

AICAR activates AMPK signaling pathways inside cells. This boosts mitochondrial biogenesis, increases fat oxidation, improves insulin sensitivity, reduces inflammation, and enhances energy production. It mimics the effects of endurance training by shifting metabolism toward fat‑burning and lean tissue preservation.

Key Functions & Core Benefits

1. Powerful Fat Loss & Metabolic Boost

   Activates AMPK to increase lipolysis and fat breakdown; elevates resting metabolic rate; reduces visceral fat and stubborn body fat; works synergistically with GLP‑1 peptides such as Tirzepatide and Retatrutide for rapid weight management.

2. Endurance Enhancement & Exercise Mimic Effect

   Improves oxygen utilization and mitochondrial function; drastically boosts stamina, stamina, and exercise tolerance; delays fatigue; enables longer training sessions. It replicates the metabolic benefits of aerobic exercise without heavy physical activity.

3. Improve Insulin Sensitivity & Blood Sugar Regulation

   Enhances glucose uptake by cells; stabilizes blood glucose levels; improves insulin resistance; supports healthy metabolic health, ideal for users on body recomposition or anti‑aging cycles.

4. Anti‑Aging & Longevity Support

   Reduces chronic inflammation and oxidative stress; improves cellular energy efficiency; supports autophagy and cellular repair; synergizes with FOXO4‑DRI senolytic peptide for comprehensive anti‑aging effects.

5. Preserve Lean Muscle Mass

   Prevents muscle loss during calorie‑deficit fat‑loss cycles; protects muscle tissue from catabolism; works well with MGF, PEG‑MGF, MK‑677 for lean‑muscle‑focused body recomposition.

6. Cardiovascular Health Improvement

   Supports healthy lipid profiles; improves blood circulation; reduces oxidative damage to blood vessels; enhances heart and cardiovascular endurance.

Standard Usage Protocol

• Dosage: 500–1000 mg daily (oral) or 200–500 mg per injection (subcutaneous)
• Frequency: Once or twice daily
• Cycle: 8–12 weeks per course
• Solvent (Injectable): Reconstitute with Sterile Water for Injection (3 mL)
• Best Timing: Taken 30–60 minutes before physical activity for maximum endurance benefits

Product Position

AICAR is a high‑performance metabolic compound supplied by SSR Biotechnology & Slimbiotech, widely used in global sports performance clinics, longevity centers, fitness optimization programs, and advanced weight‑management peptide stacks.

Research Use Only. This catalog information is reproduced from the customer legacy website. Products are not for human or veterinary use. Confirm current specification, availability and documentation before ordering.